This research is the work of Professor
Gabriel Nahas who is a member of EURAD's Scientific Advisory Board.
Prof. Nahas, MD, PhD has kindly requested that we publish this
material and we refer you to http://www.marijuana-research.com/
Title:
Scientific
Findings Prove Harms of "Soft" Drugs
Author: Alberto Carosa
Title: Scientific Findings Prove Harms of Soft
Drugs Larger Work: The Wanderer Pages: 1 and 8
Publisher & Date: Wanderer Printing Co., 201 Ohio
Street, St. Paul, MN 55107, March 8, 2001 Includes: Identical text with
no graphics.
Description
With recent campaigns to legalize marijuana sweeping the globe,
Alberto Carosa delivers information, which shows the dangers of
popular "soft" drugs. He writes, "To set the record straight, the
harms marijuana produces have been known for a long time. Now,
however, not only are these harms scientifically verifiable, but
the research has discovered that even the DNA may be impaired by
the use of ÔsoftÕ drugs." As Anti-Drug Measures FalterÉ Scientific
Findings Prove Harms Of "Soft" Drugs By Alberto Carosa Rome --
One of the various issues temporarily overshadowed by the U.S.
presidential election quagmire was the softening of anti-drug restrictions.
A string of referendums in some states accomplished this. For example,
California voters approved Proposition 36, which will bar state
courts from sentencing those convicted of simple drug possession
to prison, instead routing abusers of even heroin and cocaine into
mandatory treatment. For their part, voters in Nevada and Colorado
approved the use of "medical marijuana," while measures to make
it more difficult for the police to acquire and use the proceeds
of drug-related forfeitures were approved in Oregon and Utah. Despite
stringent federal laws, the medical use of marijuana had already
been already approved in California, Oregon, Washington, Maine,
Hawaii, and Alaska. But campaigns to loosen laws on marijuana use,
as reported by ZENIT news agency (December 23, 2001), are under
way in many other countries, from Canada to England, from Australia
to New Zealand and Italy. Their proponents argue that it is no
worse than tobacco or alcohol and that it is hypocritical to ban
this "soft" drug. Others assert that for people suffering intense
pain, marijuana may help restore appetite and improve general well
being. This trend is based on the fallacious distinction between "soft" and
hard drugs. Under this distinction, marijuana would have to be
regarded as belonging to the former category and therefore as being
innocuous. Whenever the upholders of such a distinction, including
financier George Soros who is known for pledging to "make war on
the war on drugs," are asked to offer scientific evidence of this,
what they offer amounts to propaganda. Why? For the simple reason
that the opposite is true. "Soft" drugs do not exist and marijuana
is a dangerous, harmful substance. This is an area in which science,
if it cannot prove, it can at least corroborate religious and moral
tenets, in much the same way as certain archaeological discoveries
uphold episodes in the Bible. Notably, Pope John Paul II has constantly
ruled out the liberalization of drugs. He did so as recently as
last October, when he met Fr. Pierino Gelmini with members of his
Comunita Incontro (Encounter Community), which helps young people
recover from drug dependency. On the occasion the Holy Father pointed
out that "drugs are never a solution" and the Church "intends to
reaffirm this conviction forcefully in the face of opinions favoring
the liberalization of narcotics, or at least their partial legalization
on the grounds that free access to these substances will help to
limit or reduce their harm to individuals and to society. Drugs
are not fought with drugsÉ Drugs are not overcome by drugs, but
an extensive work ... to replace the culture of death with the
culture of life" (cf. L'Osservatore Romano, English edition, November
1, 2000). As to the specific health-related aspect, the Church's
uncompromising stance is based also on the fact that no distinction
is possible between the so-called soft drugs, that is, marijuana,
and those commonly considered hard drugs such as heroin. To varying
degrees, all these illicit drugs are seriously harmful. To set
the record straight, the harms marijuana produces have been known
for a long time. Now, however, not only are these harms scientifically
verifiable, but the research has discovered that even the DNA may
be impaired by the use of "soft" drugs. These findings were made
by a top world scientist and UN consultant on narcotics, Gabriel
G. Nahas, who is a research professor of anesthesiology at the
New York University Medical Center and an adjunct professor at
the University of Paris, faculty of medicine. Dr. Nahas granted
me an exclusive interview late last fall, which is printed at the
end of this article. The interview took place on the sidelines
of the sixth annual Rainbow International Meeting in Coriano, a
picturesque location near Rimini. The Rainbow event was hosted
in the auditorium of the Comunita San Patrignano (or Sanpa, as
is more familiarly called), whose facilities for the rehabilitation
of drug addicts are probably the best in the world. Its achievements
are all the more impressive if one considers that it is a private-run
operation which is not funded by the state: 70% of its funds are
self-generated, resulting from the sale of services and products
made by its guests, ranging from ceramic tiles and pottery to book
restoration, from textile weaving to furniture, from dairy farming
to horse and dog breeding The remaining 30% comes from donations,
while the family's patients are not charged a single penny. San
Patrignano was set up in 1978, when the late Vincenzo Muccioli
started the center in a huge estate he already owned. The community
over time developed into its present form and size. In 1979 the
juridical status of the community was changed into a cooperative
and in 1985 it was incorporated as a foundation. It houses almost
2,000 people with a 75% rate of successful recoveries. After founder
Vincenzo Muccioli's death three years ago, his eldest son Andrea
took over and he is running the enterprise with his next of kin.
Andrea Muccioli is also president of the above-mentioned Rainbow
International Association Against Drugs, which San Patrignano co-founded
in August 1995, along with four other major international therapeutic
communities from Europe and North America: Basta Arbetskooperativ
of Sweden, De Hoop of Netherlands, Klub 47 of Denmark, and Vitanova
Foundation of Canada. To date, over 100 rehabilitation and therapeutic
communities around the world are members of Rainbow. Among the
keynote speakers was the president of the Italian Bishops' Conference,
Camillo Cardinal Ruini, who reaffirmed the Catholic Church's anti-liberalization
stance. He pointed out that not even one syringe was found after
the recent 15th World Youth Day, August 15-20, 2000, when over
2 million young people converged on Rome to celebrate the Jubilee
with the Holy Father. Another highlight of the Sanpa event was
the International Rainbow Award conferred on Queen Silvia of Sweden
by Antonietta Muccioli, the widow of Vincenzo. The queen received
the award for "her commitment to the concerns of youth and disadvantaged
people and for her devoted attention to the prevention of drug
abuse worldwide." A number of Italy's government ministers were
also present, including Minister of Foreign Affairs Lamberto Dini,
Minister of Justice Piero Fassino, and his colleague for parliamentary
affairs, Patrizia Toia. Pino Arlacchi, the UN Italian vice-secretary
general and head of the UN Drug Control Program, opened the proceedings.
Here follows the interview with Dr. Nahas.
Q. Dr. Nahas, you are a world scientific authority known
for your studies on marijuana and its related effects, publishing
ten books and over 200 papers. You said you had an important
finding to communicate: What is it all about?
A. These findings [on the effects of marijuana] have been known
for a long time but are still ignored. Today, on the basis of the
available evidence, it's very clear that marijuana damages the
formation of DNA in dividing cells. [DNA is the substance in the
body which carries the genetic code and which programs all cell
functions.] This impairment of DNA formation occurs in the dividing
cells of the testes. [THC, the active product of marijuana] has
been shown to impair the development of sperm cells, in man as
well as in six other animal species. These [findings] were shown
experimentally 25 years ago and have been ever since. The facts
are recorded in 12 chapters of my recent book, Marijuana and Medicine,
published in 1999 by Humana Press [Totowa, N.J.]. In spite of these
facts, many scientists, including Nobel Prize winners, are accepting
the social use of this drug, either for medical or recreational
purpose. Some are even promoting its legalization because there
is no scientific proof of the biological damage caused by marijuana.
Now the truth has finally emerged. Scientists have proven that
marijuana or THC produces early apoptosis of fast-dividing cells
of the testes and of the immunity system.
Q. What is apoptosis?
A. It is a new scientific term, which describes the "programmed
cell death" of all our cells as they grow older. Biochemically,
it is related to an impairment of DNA synthesis by the cell, triggered
from a membrane signal. It also accounts for our original finding
reported 25 years ago on the damaging effects of marijuana and
THC, its active ingredient, on sperm cells and replicating lymphocytes.
Q. Why is apoptosis so dangerous?
A. Because it is an irreversible biological process, that of cell
death. THC gives to the dividing cell of the testes, the spermatozoa,
a death signal. It gives the same death signal to the lymphocytes.
Q. Is THC also dangerous to brain cells?
A. Because THC, after it is absorbed, will first distribute in
fat, from which it is released very slowly into the blood in a
concentration, which remains toxic to the cells of the testes and
of the white blood cells, it accumulates in fat for many days after
a single dose. [It does so] for months after repeated dosingÉ Fat
is the most prevalent tissue in our body. It can store large amounts
of fat-soluble substances. The storage of marijuana [THC] in fat
has been reported in 1972 [by Nobel Prize winner J. Axelrod]. This
seminal report means that its action is very prolonged. After a
single dose of marijuana [THC], 50% of the THC will be stored in
fat for five days, and [it takes] 30 days for the complete elimination
of THC from the body. If someone takes marijuana every two days,
he will store in fat ten times more than the initial dose after
ten days and 30 times more after 30 days. These facts indicate
that there are huge reservoirs of fat for THC, from which THC will
be slowly released, and affect the cells of the immunity system,
sperm cells, and the developing fetus.
Q. And what about the brain?
A. THC attaches persistently to the membrane of the brain cell
and alters the functions of the brain, the expression of our emotions
and our thinking. This novel finding was just reported at San Patrignano,
the greatest drug rehabilitation center in the world. It was also
reported at recent scientific meetings. Marijuana and THC target
the membrane of the brain cell. That is to say the outer lining,
which protects the cell against the death signals of apoptosis,
which come from the environment. These death signals result from
a pollution of the environment and are transmitted through the
membrane to the inner part of the cell where DNA is concentrated.
THC impairs the signaling in the membrane. The membrane is a lipid
structure which signals in a positive or negative fashion to all
of the substances inside the cell and which contain DNA. DNA is
the master signaling structure, which programs all activities of
the cell. The cell membrane is a sort of filter trying to keep
away from the interior of the cell and from DNA death signals.
It is very difficult to express in simple terms the nature of those
biochemical signals. It is the first time we have a general explanation
of the mechanisms of the action of THC, which disturbs the function
of all cells. Now this mechanism, which operates at the molecular
level, is still a mystery of life. We have described with many
others the molecular events triggered by THC and which first disturb
and eventually destroy cell function and structure. THC deregulates
the signaling of the cell membrane. There is at present no physical
theory to account for the mechanism of this deregulation of brain
function by THC. This mechanism is similar to that which expresses
our conscience. We still don't understand the mechanism by which
all the digital signals converging into our brain are converted
into analog, symbolic signals. The transformation of these biochemical
digital mechanisms into analog symbolic representations is not
understood. The grave mistake of biological scientists today is
to explain every biological event by reductionist measurements
as if the brain were a computer.
Q. Is marijuana a threat to public health?
A. Yes. Consumption of marijuana creates a major problem of public
health in modern industrial societies of the West. Indeed, it threatens
the generations, which are the future of Europe since now the population
of Europe is decreasing and more and more replaced by immigrants
who also become victims of drug addiction. But even more, marijuana
threatens the capacity of future generations to conceive healthy
offspring. In Paris, Dr. Jouanet has reported that the sperm count
of men in Paris has been decreasing for the past 20 years in a
significant fashion. It is also known in fertility clinics that
samples of sperm taken from users of marijuana have high incidences
of abnormalities, which actually disqualify the donor.
Q. Do you believe that drug trafficking can be likened
to crimes against humanity?
A. Certainly, because traffickers of drugs illegally accumulate
immense wealth in selling substances which impair DNA, the patrimony
of mankind, and imperil future generations.
Q. And therefore what should be done in this regard?
A. The international United Nations Convention of 1960 banning
use, possession, and trafficking of marijuana under penalty of
law should be strictly applied in all nations in the world as it
is today in China, Japan, Singapore, Malaysia, and Myanmar. It
is also applied in Islamic countries allied to the United States
like Saudi Arabia. The law is also applied with lesser penalties
in Sweden and [other] Scandinavian countries.
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